Article
Automated high-dimensional flow cytometric data analysis.
Proceedings of the National Academy of Sciences of the United States of America - 26 May 2009
Pyne Saumyadipta, Hu Xinli, Wang Kui, Rossin Elizabeth, Lin Tsung-I, Maier Lisa M, Baecher-Allan Clare, McLachlan Geoffrey J, Tamayo Pablo, Hafler David A, De Jager Philip L, Mesirov Jill P
Abstract excerpt
Flow cytometric analysis allows rapid single cell interrogation of surface and intracellular determinants by measuring fluorescence intensity of fluorophore-conjugated reagents. The availability of new platforms, allowing detection of increasing numbers of cell surface markers, has challenged the traditional technique of identifying cell populations by manual gating and resulted in a growing need for the...
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