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Article

CAR regulates epithelial cell junction stability through control of E-cadherin trafficking

7 Oct 2013

Abstract excerpt

CAR (Coxsackie and Adenovirus Receptor) is the primary docking receptor for typeB coxsackie viruses and subgroup C adenoviruses. CAR is a member of the JAM family of adhesion receptors and is located to both tight and adherens junctions between epithelial cells where it can assemble adhesive contacts through homodimerisation in trans. However, the role of CAR in controlling epithelial junction dynamics remains...

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PMID: 24096322
DOI: 10.1038/srep02889

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