Article
A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth.
Journal of cell science - 1 Sept 2004
Excoffon Katherine J D Ashbourne, Hruska-Hageman Alesia, Klotz Michael, Traver Geri L, Zabner Joseph
Abstract excerpt
The coxsackie and adenovirus receptor (CAR) plays a role in viral infection, maintenance of the junction adhesion complex in polarized epithelia, and modulation of cellular growth properties. As a viral receptor, the C-terminus appears to play no role indicating that the major function of CAR is to tether the virus to the cell. By contrast, the C-terminus is known to play a role in cellular localization and...
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