Article
IPED: inheritance path-based pedigree reconstruction algorithm using genotype data.
Journal of computational biology : a journal of computational molecular cell biology - 1 Oct 2013
He Dan, Wang Zhanyong, Han Buhm, Parida Laxmi, Eskin Eleazar
Abstract excerpt
The problem of inference of family trees, or pedigree reconstruction, for a group of individuals is a fundamental problem in genetics. Various methods have been proposed to automate the process of pedigree reconstruction given the genotypes or haplotypes of a set of individuals. Current methods, unfortunately, are very time-consuming and inaccurate for complicated pedigrees, such as pedigrees with inbreeding. In...
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