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Article

Interaction between obesity-related genes, FTO and MC4R, associated to an increase of breast cancer risk.

Molecular biology reports - 1 Dec 2013

da Cunha Patrícia Amorim, de Carlos Back Lia Kubelka, Sereia Aline Fernanda Rodrigues, Kubelka Clara, Ribeiro Maria Cecíia Menks, Fernandes Bráulio Leal, de Souza Ilíada Rainha

Abstract excerpt

Breast cancer (BC) is a complex disease and obesity is a well-known risk factor for its development, especially after menopause. Several studies have shown Single Nucleotide Polymorphisms (SNPs) linked to overweight and obesity, such as: rs1121980 (T/C) and rs9939609 (A/T) in Fat Mass and Obesity Associated gene (FTO) and rs17782313 (T/C) in Melanocortin 4 Receptor gene (MC4R). Thus, we aimed to investigate the...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Share to Receptor, Melanocortin, Type 4

Source

Identifiers

PMID: 24091943
DOI: 10.1007/s11033-013-2780-3

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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