Article
Seasonal effects of UCP1 gene polymorphism on visceral fat accumulation in Japanese adults.
PloS one - 1 Jan 2013
Nakayama Kazuhiro, Miyashita Hiroshi, Yanagisawa Yoshiko, Iwamoto Sadahiko
Abstract excerpt
Uncoupling protein 1 (UCP1) and β3 adrenergic receptor (ADRB3) genes play central roles in the thermogenesis of brown adipose tissue (BAT) in adult humans. However, the importance of single-nucleotide polymorphisms (SNPs) in both genes during the development of obesity is controversial. Although active BAT in adult humans is frequently observed in the winter season, the effects of sampling season have not been...
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