Article
The role of uncoupling protein 2 and 3 genes polymorphism and energy expenditure in obese Indonesian children.
Journal of pediatric endocrinology & metabolism : JPEM - 1 Jan 2013
Mexitalia Maria, Yamauchi Taro, Utari Agustini, Sjarif Damayanti R, Subagio Hertanto W, Soemantri Agustinus, Ishida Takafumi
Abstract excerpt
AIM: Uncoupling protein (UCP) genes, which may contribute to energy metabolism in mitochondria, may be involved in the pathogenesis of obesity. We analyzed the differences in energy expenditure between single nucleotide polymorphisms (SNPs) UCP3-55C/T, UCP3 Y210Y, and UCP2 A55V among Indonesian children. METHODS: The study included 76 schoolchildren (36 obese and 40 healthy; mean age, 12.8 years) in Semarang,...
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