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Article

Pulmonary vein stenosis and the pathophysiology of "upstream" pulmonary veins.

The Journal of thoracic and cardiovascular surgery - 1 Jul 2014

Kato Hideyuki, Fu Yaqin Yana, Zhu Jiaquan, Wang Lixing, Aafaqi Shabana, Rahkonen Otto, Slorach Cameron, Traister Alexandra, Leung Chung Ho, Chiasson David, Mertens Luc, Benson Lee, Weisel Richard D, Hinz Boris, Maynes Jason T, Coles John G, Caldarone Christopher A

Abstract excerpt

BACKGROUND: Surgical and catheter-based interventions on pulmonary veins are associated with pulmonary vein stenosis (PVS), which can progress diffusely through the "upstream" pulmonary veins. The mechanism has been rarely studied. We used a porcine model of PVS to assess disease progression with emphasis on the potential role of endothelial-mesenchymal transition (EndMT). METHODS: Neonatal piglets underwent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24084286
DOI: 10.1016/j.jtcvs.2013.08.046

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