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Article

Cutaneous dermal Ia+ cells are capable of initiating delayed type hypersensitivity responses.

The Journal of investigative dermatology - 1 Mar 1990

Tse Y, Cooper K D

Abstract excerpt

The presence of Langerhans cells (LC) within the epidermis has been shown to be critical for inducing T-cell-mediated immune responses in the skin. The purpose of this study was to assess whether cells in the dermis can initiate T-cell-mediated delayed-type hypersensitivity responses in vivo. Initially, back skins from C3H mice were trypsinized to remove the epidermis. The dermis was enzymatically dispersed and...

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Identifiers

PMID: 2407786
DOI: 10.1111/1523-1747.ep12874114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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