Article
Cutaneous dermal Ia+ cells are capable of initiating delayed type hypersensitivity responses.
The Journal of investigative dermatology - 1 Mar 1990
Tse Y, Cooper K D
Abstract excerpt
The presence of Langerhans cells (LC) within the epidermis has been shown to be critical for inducing T-cell-mediated immune responses in the skin. The purpose of this study was to assess whether cells in the dermis can initiate T-cell-mediated delayed-type hypersensitivity responses in vivo. Ini...
Topics
- Animals
- Antigen-Presenting Cells
- Cytological Techniques
- Dermatitis, Contact
- Endopeptidases
- Hair
- Histocompatibility Antigens Class II
- Hypersensitivity, Delayed
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H