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Article

Functional effect of Saffron supplementation and risk genotypes in early age-related macular degeneration: a preliminary report.

Journal of translational medicine - 25 Sept 2013

Marangoni Dario, Falsini Benedetto, Piccardi Marco, Ambrosio Lucia, Minnella Angelo Maria, Savastano Maria Cristina, Bisti Silvia, Maccarone Rita, Fadda Antonello, Mello Enrica, Concolino Paola, Capoluongo Ettore

Abstract excerpt

BACKGROUND: To determine whether the functional effects of oral supplementation with Saffron, a natural compound that proved to be neuroprotective in early age-related macular degeneration, are influenced by complement factor H (CFH) and age-related maculopathy susceptibility 2 (ARMS2) risk genotypes. METHODS: Thirty-three early AMD patients, screened for CFH (rs1061170) and ARMS2 (rs10490924) polymorphisms and...

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Identifiers

PMID: 24067115
DOI: 10.1186/1479-5876-11-228
PMCID: PMC3850693

Genes

ARMS2
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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