Article
Restriction genes for retroviruses influence the risk of multiple sclerosis.
PloS one - 1 Jan 2013
Nexø Bjørn A, Hansen Bettina, Nissen Kari K, Gundestrup Lisa, Terkelsen Thorkild, Villesen Palle, Bahrami Shervin, Petersen Thor, Pedersen Finn S, Laska Magdalena J
Abstract excerpt
We recently described that the autoimmune, central nervous system disease, multiple sclerosis (MS), is genetically associated with the human endogenous retroviral locus, HERV-Fc1, in Scandinavians. A number of dominant human genes encoding factors that restrict retrovirus replication have been known for a long time. Today human restriction genes for retroviruses include amongst others TRIMs, APOBEC3s, BST2 and...
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