Article
Independent parallel functions of p19 plant viral suppressor of RNA silencing required for effective suppressor activity.
Nucleic acids research - 1 Jan 2014
Várallyay Éva, Oláh Eniko, Havelda Zoltán
Abstract excerpt
Plant viruses ubiquitously mediate the induction of miR168 trough the activities of viral suppressors of RNA silencing (VSRs) controlling the accumulation of ARGONAUTE1 (AGO1), one of the main components of RNA silencing based host defence system. Here we used a mutant Tombusvirus p19 VSR (p19-3M) disabled in its main suppressor function, small interfering RNA (siRNA) binding, to investigate the biological role...
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