Article
The in vitro and in vivo effects of a low-molecular-weight fucoidan on the osteogenic capacity of human adipose-derived stromal cells.
Tissue engineering. Part A - 1 Jan 2014
Pereira Jessica, Portron Sophie, Dizier Blandine, Vinatier Claire, Masson Martial, Sourice Sophie, Galy-Fauroux Isabelle, Corre Pierre, Weiss Pierre, Fischer Anne-Marie, Guicheux Jérôme, Helley Dominique
Abstract excerpt
Human adipose-derived stromal cells (hASCs) may hold potential for bone tissue engineering. Osteogenic differentiation of these cells is crucial to bone formation. Low-molecular-weight fucoidan (LMWF) is a sulfated polysaccharide that potentiates several growth factors, including pro-angiogenic growth factors. To investigate whether hASC preconditioning with LMWF promoted bone repair, we compared the effects of...
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