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Article

Unisexual reproduction reverses Muller's ratchet.

Genetics - 1 Nov 2014

Roach Kevin C, Heitman Joseph

Abstract excerpt

Cryptococcus neoformans is a pathogenic basidiomycetous fungus that engages in outcrossing, inbreeding, and selfing forms of unisexual reproduction as well as canonical sexual reproduction between opposite mating types. Long thought to be clonal, >99% of sampled environmental and clinical isolates of C. neoformans are MATα, limiting the frequency of opposite mating-type sexual reproduction. Sexual reproduction...

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Identifiers

PMID: 25217049
DOI: 10.1534/genetics.114.170472
PMCID: PMC4224152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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