Identifying potential drug targets in hepatocellular carcinoma based on network analysis and one-class support vector machine

Abstract excerpt

Hepatocellular carcinoma (HCC) is one major cause of cancer-related death worldwide. But now, the systematic therapy for the advanced stages of HCC is rather limited. Thus, the discovery of novel drug targets and thereafter targeted drugs against HCC is continuously needed. In this study, we combined clinical association data, gene expression profiles and manually collected drug target genes with the human...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bioinformatics and Genomic Networks
• Share to Computational Drug Discovery Methods
• Share to Ferroptosis and cancer prognosis