Article
The association of a single-nucleotide polymorphism in CUBN and the risk of albuminuria and cardiovascular disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Feb 2014
McMahon Gearoid M, O'Seaghdha Conall M, Hwang Shih-Jen, Meigs James B, Fox Caroline S
Abstract excerpt
BACKGROUND: Albuminuria is an important risk factor for cardiovascular disease (CVD). We have previously identified a missense single-nucleotide polymorphism (rs1801239) in the CUBN gene that is associated with albuminuria. Whether albuminuria is associated with CVD in the presence of the CUBN mutation is unknown. METHODS: We analyzed participants from the Framingham Heart Study (n=6399, mean age 47 years, 53.4%...
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