Article
Epigenetics: novel mechanism of pulmonary hypertension.
Lung - 1 Dec 2013
Huang Jing-bin, Liang Jian, Zhao Xiao-fang, Wu Wen-sen, Zhang Fu
Abstract excerpt
INTRODUCTION: Epigenetics refers to changes in phenotype and gene expression that occur without alterations in DNA sequence. MicroRNAs are relatively recently discovered negative regulators of gene expression and act at the posttranscriptional level. METHODS: This review summarizes epigenetic mechanisms of pulmonary hypertension, focusing on microRNAs related to pulmonary hypertension. RESULTS: There are three...
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