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The Continued Absence of Functional Germline Stem Cells in Adult Ovaries

25 Sept 2022

Abstract excerpt

Ovaries are central to development, fertility, and reproduction of women. A particularly interesting feature of ovaries is their accelerated aging compared to other tissues, leading to loss of function far before other organs senesce. The limited pool of ovarian follicles is generated before birth and once exhausted, menopause will inevitably commence around the age of 50 years marking the end of fertility. Yet,...

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PMID: 36153824
DOI: 10.1093/stmcls/sxac070

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