Article
Downregulation of miR-151-5p contributes to increased susceptibility to arrhythmogenesis during myocardial infarction with estrogen deprivation.
PloS one - 1 Jan 2013
Zhang Ying, Wang Renjun, Du Weijie, Wang Shuxuan, Yang Lei, Pan Zhenwei, Li Xuelian, Xiong Xuehui, He Hua, Shi Yongfang, Liu Xue, Yu Shaonan, Bi Zhengang, Lu Yanjie, Shan Hongli
Abstract excerpt
Estrogen deficiency is associated with increased incidence of cardiovascular diseases. But merely estrogen supplementary treatment can induce many severe complications such as breast cancer. The present study was designed to elucidate molecular mechanisms underlying increased susceptibility of arrhythmogenesis during myocardial infarction with estrogen deprivation, which provides us a new target to cure cardiac...
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