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Article

Fibrillin-1 directly regulates osteoclast formation and function by a dual mechanism

13 Sept 2013

Abstract excerpt

Mutations in the fibrillin-1 gene give rise to a number of heritable disorders, which are all characterized by various malformations of bone as well as manifestations in other tissues. However, the role of fibrillin-1 in the development and homeostasis of bone is not well understood. Here, we examined the role of fibrillin-1 in regulating osteoclast differentiation from primary bone-marrow-derived precursors and...

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PMID: 24039232
DOI: 10.1242/jcs.127571

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