Article
Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2013
McGrath Lauren M, Cornelis Marilyn C, Lee Phil H, Robinson Elise B, Duncan Laramie E, Barnett Jennifer H, Huang Jie, Gerber Gloria, Sklar Pamela, Sullivan Patrick, Perlis Roy H, Smoller Jordan W
Abstract excerpt
Functional impairment is one of the most enduring, intractable consequences of psychiatric disorders and is both familial and heritable. Previous studies have suggested that variation in functional impairment can be independent of symptom severity. Here we report the first genome-wide association study (GWAS) of functional impairment in the context of major mental illness. Participants of European-American...
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