Article
Discriminating dominant computed tomography phenotypes in smokers without or with mild COPD.
Respiratory medicine - 1 Jan 2014
Mohamed Hoesein Firdaus A A, Schmidt Michael, Mets Onno M, Gietema Hester A, Lammers Jan-Willem J, Zanen Pieter, de Koning Harry J, van der Aalst Carlijn, Oudkerk Matthijs, Vliegenthart Rozemarijn, Isgum Ivana, Prokop Mathias, van Ginneken Bram, van Rikxoort Eva M, de Jong Pim A
Abstract excerpt
BACKGROUND: Finding phenotypes within COPD patients may prove imperative for optimizing treatment and prognosis. We hypothesized that it would be possible to discriminate emphysematous, large airway wall thickening and small airways disease dominant phenotypes. METHODS: Inspiratory and expiratory CTs were performed in 1140 male smokers without or with mild COPD to quantify emphysema, airway wall thickness and air...
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