Article
A mixed phenotype of airway wall thickening and emphysema is associated with dyspnea and hospitalization for chronic obstructive pulmonary disease.
Annals of the American Thoracic Society - 1 Jul 2015
Van Tho Nguyen, Ogawa Emiko, Trang Le Thi Huyen, Ryujin Yasushi, Kanda Rie, Nakagawa Hiroaki, Goto Kenichi, Fukunaga Kentaro, Higami Yuichi, Seto Ruriko, Wada Hiroshi, Yamaguchi Masafumi, Nagao Taishi, Lan Le Thi Tuyet, Nakano Yasutaka
Abstract excerpt
RATIONALE: Quantitative computed tomography (CT) has been used to phenotype patients with chronic obstructive pulmonary disease (COPD). A mixed phenotype is defined as the presence of both airway wall thickening and emphysema on quantitative CT. Little is known about patients with COPD with the mixed phenotype. OBJECTIVES: To propose a method of phenotyping COPD based on quantitative CT and to compare clinically...
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