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Characterization ofHOXgene expression in canine mammary tumour cell lines from spontaneous tumours

6 Sept 2013

Abstract excerpt

Spatial/temporal controls of development are regulated by the homeotic (HOX) gene complex and require integration with oncogenes and tumour suppressors regulating cell cycle exit. Spontaneously derived neoplastic canine mammary carcinoma cell models were investigated to determine if HOX expression profiles were associated with neoplasia as HOX genes promote neoplastic potential in human cancers. Comparative...

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PMID: 24034269
DOI: 10.1111/vco.12062

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