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Article

Comparative transcriptional profiling of canine acanthomatous ameloblastoma and homology with human ameloblastoma.

Scientific reports - 7 Sept 2021

Peralta Santiago, Duhamel Gerald E, Katt William P, Heikinheimo Kristiina, Miller Andrew D, Ahmed Faraz, McCleary-Wheeler Angela L, Grenier Jennifer K

Abstract excerpt

Ameloblastomas are odontogenic tumors that are rare in people but have a relatively high prevalence in dogs. Because canine acanthomatous ameloblastomas (CAA) have clinicopathologic and molecular features in common with human ameloblastomas (AM), spontaneous CAA can serve as a useful translational model of disease. However, the molecular basis of CAA and how it compares to AM are incompletely understood. In this...

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Identifiers

PMID: 34493785
DOI: 10.1038/s41598-021-97430-0
PMCID: PMC8423744

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