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Article

RRM1 and RRM2 pharmacogenetics: association with phenotypes in HapMap cell lines and acute myeloid leukemia patients.

Pharmacogenomics - 1 Sept 2013

Cao Xueyuan, Mitra Amit K, Pounds Stanley, Crews Kristine R, Gandhi Varsha, Plunkett William, Dolan M Eileen, Hartford Christine, Raimondi Susana, Campana Dario, Downing James, Rubnitz Jeffrey E, Ribeiro Raul C, Lamba Jatinder K

Abstract excerpt

BACKGROUND: Ribonucleotide reductase catalyzes an essential step in the cellular production of deoxyribonucleotide triphosphates and has been associated with clinical outcome in cancer patients receiving nucleoside analog-based chemotherapy. MATERIALS & METHODS: In the current study, we sequenced the genes RRM1 and RRM2 in genomic DNA from HapMap cell lines with European (Utah residents with northern and western...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24024897
DOI: 10.2217/pgs.13.131
PMCID: PMC3860742

Genes

RRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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