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Article

Role of Sirtuins in Stem Cell Differentiation

26 Feb 2013

Abstract excerpt

Sirtuins play an essential role in the cellular response to environmental stress, promoting DNA repair, telomere stability, cell cycle arrest, cellular senescence, and apoptosis. Much attention has been given to the role of sirtuins in aging and cancer development; however, less is known about their role in stem cell regulation. This review focuses in this topic and discusses the possible implications in adult...

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PMID: 24020001
DOI: 10.1177/1947601913479798

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