The repertoire of MHC class I genes in the common marmoset: evidence for functional plasticity.

doi:10.1007/s00251-013-0732-7

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Article

The repertoire of MHC class I genes in the common marmoset: evidence for functional plasticity.

Immunogenetics - 1 Dec 2013

van der Wiel Marit K, Otting Nel, de Groot Natasja G, Doxiadis Gaby G M, Bontrop Ronald E

Abstract excerpt

In humans, the classical antigen presentation function of major histocompatibility complex (MHC) class I molecules is controlled by the human leukocyte antigen HLA -A, HLA-B and HLA-C loci. A similar observation has been made for great apes and Old World monkey species. In contrast, a New World monkey species such as the cotton-top tamarin (Saguinus oedipus) appears to employ the G locus for its classical antigen...

Topics

Alleles
Animals
Callithrix
Evolution, Molecular
Genes, MHC Class I
HLA-G Antigens
Humans
Phylogeny
Sequence Alignment
Sequence Homology, Amino Acid

Source

Open in PubMed

Identifiers

PMID: 24018468
DOI: 10.1007/s00251-013-0732-7

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