Article
MHC class I genes in the owl monkey: mosaic organisation, convergence and loci diversity.
Immunogenetics - 1 Feb 2005
Cardenas Paula P, Suarez Carlos F, Martinez Pilar, Patarroyo Manuel E, Patarroyo Manuel A
Abstract excerpt
The MHC class I molecule plays an important role in immune response, pathogen recognition and response against vaccines and self- versus non-self-recognition. Studying MHC class I characteristics thus became a priority when dealing with Aotus to ensure its use as an animal model for biomedical research. Isolation, cloning and sequencing of exons 1-8 from 27 MHC class I alleles obtained from 13 individuals...
Topics
- Amino Acid Sequence
- Animals
- Aotidae
- Base Sequence
- Cloning, Molecular
- Codon, Nonsense
- DNA, Complementary
- Evolution, Molecular
- Genetic Variation
- Histocompatibility Antigens Class I
- Molecular Sequence Data
- Phylogeny