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Article

Evidence of In Vitro Preservation of Human Nephrogenesis at the Single-Cell Level

25 May 2017

Abstract excerpt

During nephrogenesis, stem/progenitor cells differentiate and give rise to early nephron structures that segment to proximal and distal nephron cell types. Previously, we prospectively isolated progenitors from human fetal kidney (hFK) utilizing a combination of surface markers. However, upon culture nephron progenitors differentiated and could not be robustly maintained in vitro. Here, by culturing hFK in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28552604
DOI: 10.1016/j.stemcr.2017.04.026

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