Article
Kidney side population reveals multilineage potential and renal functional capacity but also cellular heterogeneity.
Journal of the American Society of Nephrology : JASN - 1 Jul 2006
Challen Grant A, Bertoncello Ivan, Deane James A, Ricardo Sharon D, Little Melissa H
Abstract excerpt
Side population (SP) cells in the adult kidney are proposed to represent a progenitor population. However, the size, origin, phenotype, and potential of the kidney SP has been controversial. In this study, the SP fraction of embryonic and adult kidneys represented 0.1 to 0.2% of the total viable cell population. The immunophenotype and the expression profile of kidney SP cells was distinct from that of bone...
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