Article
Phenotypic alterations in human saphenous vein culture induced by tumor necrosis factor-alpha and lipoproteins: a preliminary development of an initial atherosclerotic plaque model.
Lipids in health and disease - 8 Sept 2013
Prasongsukarn Kriengchai, Chaisri Urai, Chartburus Peenutchanee, Wetchabut Kamolwan, Benjathummarak Surachet, Khachansaksumet Vasant, Maneerat Yaowapa
Abstract excerpt
BACKGROUND: Atherosclerosis is a chronic progressive inflammatory disease of blood vessels particularly the arteries. The development of atherosclerotic plaques or atherogenesis is a complex process that is influenced by cardiovascular risk factors such as vascular inflammation and dyslipidemia. This study demonstrates the ability of tumor necrosis factor-alpha (TNF-α) and low density lipoproteins (LDL) to induce...
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