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Article

Single-molecule spectroscopy of cold denaturation and the temperature-induced collapse of unfolded proteins.

Journal of the American Chemical Society - 25 Sept 2013

Aznauryan Mikayel, Nettels Daniel, Holla Andrea, Hofmann Hagen, Schuler Benjamin

Abstract excerpt

Recent Förster resonance energy transfer (FRET) experiments show that heat-unfolded states of proteins become more compact with increasing temperature. At the same time, NMR results indicate that cold-denatured proteins are more expanded than heat-denatured proteins. To clarify the connection bet...

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Source

Identifiers

PMID: 24010673
DOI: 10.1021/ja407009w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24010673-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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