Article
Gene-based polymorphisms, genomic organization of interferon-β promoter stimulator 1 (IPS-1) gene and association study with the natural resistance to grass carp reovirus in grass carp Ctenopharyngodon idella.
Developmental and comparative immunology - 1 Dec 2013
Wan Quanyuan, Su Jianguo, Chen Xiaohui, Yang Chunrong
Abstract excerpt
Interferon-β promoter stimulator 1 (IPS-1) plays a pivotal role in the production of type I interferon (IFN) and pro-inflammatory cytokines. Though its function in innate immunity was widely studied, its genetic polymorphisms and evolution information were rarely known. Herein, the present study firstly identified and characterized the genomic organization of CiIPS-1 (IPS-1 gene of grass carp, Ctenopharyngodon...
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