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Novel goose parvovirus VP1 targets IRF7 protein to block the type I interferon upstream signaling pathway

6 Jul 2024

Abstract excerpt

Outbreaks of short beak and dwarfism syndrome (SBDS), caused by a novel goose parvovirus (NGPV), have occurred in China since 2015. The NGPV, a single-stranded DNA virus, is thought to be vertically transmitted. However, the mechanism of NGPV immune evasion remains unclear. In this study, we investigated the impact of NGPV infection on the Cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING)...

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PMID: 39043024
DOI: 10.1016/j.psj.2024.104065

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