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Article

Novel TRAF1‐ALK fusion identified by deep RNA sequencing of anaplastic large cell lymphoma

2 Sept 2013

Abstract excerpt

Chromosomal translocations leading to expression of abnormal fusion proteins play a major role in the pathogenesis of various hematologic malignancies. The recent development of high-throughput, "deep" sequencing has allowed discovery of novel translocations leading to a rapid increase in understanding these diseases. Translocations involving the anaplastic lymphoma kinase (ALK) gene leading to ALK fusion...

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PMID: 23999969
DOI: 10.1002/gcc.22104

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