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Article

ALK-positive large B-cell lymphoma: a clinicopathological and molecular characteristics analysis of seven cases.

Pathology - 1 Dec 2024

Wang Xuan, Yi Hongmei, Liu Qingxiao, Guo Tuanjie, Li Anqi, Ouyang Binshen, Li Yimin, Zhang Yuxiu, Xu Haimin, Dong Lei, Wang Xu, Wang Chaofu

Abstract excerpt

Anaplastic lymphoma kinase-positive large B-cell lymphoma (ALK+ LBCL) is a rare and highly aggressive lymphoma with characteristic ALK rearrangements. Various fusion genes involving ALK have been demonstrated, but the influence of the ALK fusion partners on ALK protein expression and the genetic characteristics of ALK+ LBCL remain relatively unknown. In this study, we conducted an extensive clinicopathological...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39237383
DOI: 10.1016/j.pathol.2024.05.014

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