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Article

Association between corticotropin-releasing hormone receptor 1 and 2 (CRHR1 and CRHR2) gene polymorphisms and personality traits.

Psychiatric genetics - 1 Dec 2013

Ishitobi Yoshinobu, Nakayama Shinya, Kanehisa Masayuki, Higuma Haruka, Maruyama Yoshihiro, Okamoto Shizuko, Inoue Ayako, Imanaga Junko, Tanaka Yoshihiro, Tsuru Jusen, Hanada Hiroaki, Akiyoshi Jotaro

Abstract excerpt

Previous studies have reported that the hypothalamic-pituitary-adrenal axis is involved with personality traits. We examined the association between corticotropin-releasing hormone receptor (CRHR) genes and personality traits. We investigated the 12 single-nucleotide polymorphisms of intron CRHR (six in CRHR1 and six in CRHR2, respectively) in 218 healthy volunteers using TaqMan PCR assays. Personality traits...

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Source

Identifiers

PMID: 23982282
DOI: 10.1097/YPG.0000000000000002

Genes

CRHR1
CRHR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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