Article
Effect of the cytochrome P450 19 (aromatase) gene polymorphism on personality traits in healthy subjects.
Behavioural brain research - 14 Dec 2009
Matsumoto Yoshihiko, Suzuki Akihito, Shibuya Naoshi, Sadahiro Ryoichi, Kamata Mitsuhiro, Goto Kaoru, Otani Koichi
Abstract excerpt
There have been several studies showing the relationship between sex hormones and personality traits. Cytochrome P450 19 (CYP 19, aromatase) is the rate-limiting enzyme for the conversion of androgens into estrogens, and it has been reported that the C/T single nucleotide polymorphism in the 3'-untranslated region (3'UTR) of CYP19 gene (rs10046) affects dispositions of estradiol and testosterone. Therefore, it is...
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