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TOC1: Characterization of a Selective Oligomeric Tau Antibody

24 Sept 2013

Abstract excerpt

The work presented herein addresses a specific portion of the tau pathology, pre-fibrillar oligomers, now thought to be important pathological components in Alzheimer's disease and other neurodegenerative tauopathies. In previous work, we generated an antibody against purified recombinant cross-linked tau dimers, called Tau Oligomeric Complex 1 (TOC1). TOC1 recognizes tau oligomers and its immunoreactivity is...

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PMID: 23979027
DOI: 10.3233/jad-131235

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