Article
Nitrogen source-dependent capsule induction in human-pathogenic cryptococcus species.
Eukaryotic cell - 1 Nov 2013
Frazzitta Aubrey E, Vora Haily, Price Michael S, Tenor Jennifer L, Betancourt-Quiroz Marisol, Toffaletti Dena L, Cheng Nan, Perfect John R
Abstract excerpt
Cryptococcus neoformans and C. gattii cause meningoencephalitis and are an increasing human health threat. These pathogenic Cryptococcus species are neurotropic and persist in the cerebrospinal fluid (CSF) of the mammalian host during infection. In order to survive in the host, pathogenic fungi must procure nutrients, such as carbon and nitrogen, from the CSF. To enhance our understanding of nutrient acquisition...
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