Article
Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis.
Cold Spring Harbor perspectives in medicine - 1 Jul 2014
Kwon-Chung Kyung J, Fraser James A, Doering Tamara L, Wang Zhou, Janbon Guilhem, Idnurm Alexander, Bahn Yong-Sun
Abstract excerpt
Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished from other pathogenic yeasts such as Candida by the presence of a polysaccharide capsule, formation of melanin, and urease activity, which all function as virulence determinants. Infection proceeds via inhalation and subsequent dissemination to...
Topics
- Cryptococcosis
- Cryptococcus gattii
- Cryptococcus neoformans
- Drug Resistance, Multiple, Fungal
- Enzymes
- Fungal Capsules
- Genotype
- Host-Pathogen Interactions
- Humans
- Life Cycle Stages
