Article
A microRNA polycistron as a potential human oncogene.
Nature - 9 Jun 2005
He Lin, Thomson J Michael, Hemann Michael T, Hernando-Monge Eva, Mu David, Goodson Summer, Powers Scott, Cordon-Cardo Carlos, Lowe Scott W, Hannon Gregory J, Hammond Scott M
Abstract excerpt
To date, more than 200 microRNAs have been described in humans; however, the precise functions of these regulatory, non-coding RNAs remains largely obscure. One cluster of microRNAs, the mir-17-92 polycistron, is located in a region of DNA that is amplified in human B-cell lymphomas. Here we comp...
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