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Article

microRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma

26 Jun 2013

Abstract excerpt

Anaplastic large-cell lymphomas (ALCLs) encompass at least 2 systemic diseases distinguished by the presence or absence of anaplastic lymphoma kinase (ALK) expression. We performed genome-wide microRNA (miRNA) profiling on 33 ALK-positive (ALK[+]) ALCLs, 25 ALK-negative (ALK[-]) ALCLs, 9 angioimmunoblastic T-cell lymphomas, 11 peripheral T-cell lymphomas not otherwise specified (PTCLNOS), and normal T cells, and...

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PMID: 23801630
DOI: 10.1182/blood-2012-08-447375

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