Article
[Detection of resistance mutations in chronic hepatitis B patients receiving antiviral therapy for over one year].
Mikrobiyoloji bulteni - 1 Jul 2013
Aydoğan Sibel, Ergünay Koray, Balaban Yasemin, Alp Alpaslan, Simşek Halis, Tatar Gonca, Hasçelik Gülşen, Us Dürdal
Abstract excerpt
Primary mutations conferring hepatitis B virus (HBV) antiviral resistance and associated secondary/compensatory mutations were investigated in this study by DNA sequencing (SEQ) and two commercial Line Probe Assays (LiPAs) (Inno-Lipa HBV DRv2 and Inno-Lipa HBV DRv3, Innogenetics, Belgium). A total of 71 subjects under follow-up for chronic hepatitis B and receiving lamivudine (LVD) therapy for one year or longer...
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