Article
[Resistance in hepatitis B virus].
Enfermedades infecciosas y microbiologia clinica - 1 May 2008
Sheldon Julie, Sarmento E Castro Rui, Soriano Vicente
Abstract excerpt
The development hepatitis B virus (HBV) polymerase inhibitors has revolutionised the treatment of chronic HBV infection. However, the emergence of resistance mutations can compromise their clinical efficacy and it is mandatory to know the mechanisms of these resistances, its clinical implications, strategies for prevention and how to deal with the rescue. Since HBV has a high degree of replication and a high...
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