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Article

Identification of transcriptional subgroups in EGFR-mutated and EGFR/KRAS wild-type lung adenocarcinoma reveals gene signatures associated with patient outcome.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2013

Planck Maria, Isaksson Sofi, Veerla Srinivas, Staaf Johan

Abstract excerpt

PURPOSE: In lung adenocarcinoma, EGFR and KRAS mutations dominate the mutational spectrum and have clear therapeutic implications. We sought to determine whether transcriptional subgroups of clinical relevance exist within EGFR-mutated, KRAS-mutated, or EGFR and KRAS wild-type (EGFRwt/KRASwt) ade...

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Source

Identifiers

PMID: 23938291
DOI: 10.1158/1078-0432.CCR-13-0928

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23938291-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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