Article
Haplogroup T is an obesity risk factor: mitochondrial DNA haplotyping in a morbid obese population from southern Italy.
BioMed research international - 1 Jan 2013
Nardelli Carmela, Labruna Giuseppe, Liguori Rosario, Mazzaccara Cristina, Ferrigno Maddalena, Capobianco Valentina, Pezzuti Massimo, Castaldo Giuseppe, Farinaro Eduardo, Contaldo Franco, Buono Pasqualina, Sacchetti Lucia, Pasanisi Fabrizio
Abstract excerpt
Mitochondrial DNA (mtDNA) haplogroups have been associated with the expression of mitochondrial-related diseases and with metabolic alterations, but their role has not yet been investigated in morbid obese Caucasian subjects. Therefore, we investigated the association between mitochondrial haplogroups and morbid obesity in patients from southern Italy. The mtDNA D-loop of morbid obese patients (n = 500; BMI > 40...
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