Article
Association between manganese superoxide dismutase (MnSOD) gene polymorphism and elderly obesity.
Molecular and cellular biochemistry - 1 Aug 2009
Montano Marco Aurélio Echart, Barrio Lera Juan Pablo, Gottlieb Maria Gabriela Valle, Schwanke Carla Helena Augustin, da Rocha Maria Izabel Ugalde Marques, Manica-Cattani Maria Fernanda, dos Santos Greice Feyl, da Cruz Ivana Beatrice Manica
Abstract excerpt
Evidence suggests an association between obesity and oxidative stress caused by superoxide production. Since the dismutation of superoxide is catalyzed by superoxide dismutase enzymes, we tested the association between obesity and Ala16Val manganese-dependent superoxide dismutase gene (MnSOD) polymorphism. We analyzed 815 free-living community subjects (> or =60 years old) grouped into subjects who were either...
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