Article
A replication study from Chinese supports association between lupus-risk allele in TNFSF4 and renal disorder.
BioMed research international - 1 Jan 2013
Zhou Xu-jie, Cheng Fa-juan, Qi Yuan-yuan, Zhao Ming-hui, Zhang Hong
Abstract excerpt
A recent phenotypic association study of genetic susceptibility loci in SLE suggested that TNFSF4 gene might be useful to predict renal disorder in lupus patients. To replicate the association, two single-nucleotide polymorphisms (SNPs: rs2205960 and rs10489265) were genotyped in 814 SLE patients. Correlations between genotypes and TNFSF4 expression were determined. The stainings of TNFSF4 in renal biopsy...
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